| 2022-04-30 17:00:0030 april 2022 | SK Lochristi  | 2 - 1 |  Avanti Stekene | 17:00:0017:00 | N/A |
| 2022-04-24 15:00:0024 april 2022 | KVK Svelta Melsele  | 3 - 4 | SK Lochristi | 15:00:0015:00 | N/A |
| 2022-04-16 15:00:0016 april 2022 | KHO Wolvertem-Merchtem  | 4 - 0 | SK Lochristi | 15:00:0015:00 | N/A |
| 2022-04-10 15:00:0010 april 2022 | SK Lochristi | 0 - 0 |  KFC Eppegem | 15:00:0015:00 | N/A |
| 2022-04-02 18:30:002 april 2022 | Erpe-Mere United  | 1 - 3 | SK Lochristi | 18:30:0018:30 | N/A |
| 2022-03-27 15:00:0027 maart 2022 | SK Lochristi | 1 - 2 |  KVC Jong Lede | 15:00:0015:00 | N/A |
| 2022-03-19 19:30:0019 maart 2022 | SK Sint-Niklaas  | 0 - 6 | SK Lochristi | 19:30:0019:30 | N/A |
| 2022-03-13 15:00:0013 maart 2022 | SK Lochristi | 0 - 2 |  FC Lebbeke | 15:00:0015:00 | N/A |
| 2022-03-06 15:00:006 maart 2022 | VW Hamme  | 0 - 1 | SK Lochristi | 15:00:0015:00 | N/A |
| 2022-02-27 15:00:0027 februari 2022 | SK Lochristi | 4 - 3 |  SV Oostkamp | 15:00:0015:00 | N/A |
| 2022-02-20 15:00:0020 februari 2022 | SK Lochristi | 2 - 0 |  KFC Voorde-Appelterre | 15:00:0015:00 | N/A |
| 2022-02-13 15:00:0013 februari 2022 | SK Lochristi | 1 - 2 |  TEMPO Overijse | 15:00:0015:00 | N/A |
| 2022-02-06 15:00:006 februari 2022 | SV Anzegem  | 1 - 1 | SK Lochristi | 15:00:0015:00 | N/A |
| 2022-01-30 14:30:0030 januari 2022 | SK Lochristi | 2 - 1 |  Rhodienne De Hoek | 14:30:0014:30 | N/A |
| 2021-12-18 19:30:0018 december 2021 | KM Torhout  | 3 - 2 | SK Lochristi | 19:30:0019:30 | N/A |
| 2021-12-12 15:00:0012 december 2021 | Avanti Stekene | 2 - 2 | SK Lochristi | 15:00:0015:00 | N/A |
| 2021-12-05 14:30:005 december 2021 | SK Lochristi | 2 - 2 | KVK Svelta Melsele | 14:30:0014:30 | N/A |
| 2021-11-28 14:30:0028 november 2021 | KFC Eppegem | 3 - 2 | SK Lochristi | 14:30:0014:30 | N/A |
| 2021-11-21 14:30:0021 november 2021 | SK Lochristi | 1 - 2 | Erpe-Mere United | 14:30:0014:30 | N/A |
| 2021-11-14 14:30:0014 november 2021 | KVC Jong Lede | 1 - 2 | SK Lochristi | 14:30:0014:30 | N/A |
| 2021-11-07 14:30:007 november 2021 | SK Lochristi | 4 - 0 | SK Sint-Niklaas | 14:30:0014:30 | N/A |
| 2021-10-30 20:00:0030 oktober 2021 | FC Lebbeke | 2 - 1 | SK Lochristi | 20:00:0020:00 | N/A |
| 2021-10-24 15:00:0024 oktober 2021 | SK Lochristi | 2 - 2 | VW Hamme | 15:00:0015:00 | N/A |
| 2021-10-17 15:00:0017 oktober 2021 | KFC Voorde-Appelterre | 3 - 0 | SK Lochristi | 15:00:0015:00 | N/A |
| 2021-10-09 20:00:009 oktober 2021 | TEMPO Overijse | 0 - 1 | SK Lochristi | 20:00:0020:00 | N/A |
| 2021-10-03 15:00:003 oktober 2021 | SK Lochristi | 3 - 2 | SV Anzegem | 15:00:0015:00 | N/A |
| 2021-09-26 16:00:0026 september 2021 | Rhodienne De Hoek | 2 - 0 | SK Lochristi | 16:00:0016:00 | N/A |
| 2021-09-19 15:00:0019 september 2021 | SK Lochristi | 4 - 0 | KHO Wolvertem-Merchtem | 15:00:0015:00 | N/A |
| 2021-09-11 19:30:0011 september 2021 | SV Oostkamp | 2 - 2 | SK Lochristi | 19:30:0019:30 | N/A |
| 2021-09-05 15:00:005 september 2021 | SK Lochristi | 5 - 1 | KM Torhout | 15:00:0015:00 | N/A |
| 2021-02-20 20:00:0020 februari 2021 | TEMPO Overijse | - | SK Lochristi | 20:00:00Geannuleerd | N/A |
| 2021-02-14 15:00:0014 februari 2021 | SK Lochristi | - | KM Torhout | 15:00:00Geannuleerd | N/A |
| 2020-12-13 14:30:0013 december 2020 | KVC Jong Lede | - | SK Lochristi | 14:30:00Geannuleerd | N/A |
| 2020-12-06 14:30:006 december 2020 | SK Lochristi | - | Avanti Stekene | 14:30:00Geannuleerd | N/A |
| 2020-11-29 14:30:0029 november 2020 | KHO Wolvertem-Merchtem | - | SK Lochristi | 14:30:00Geannuleerd | N/A |
| 2020-11-22 14:30:0022 november 2020 | SK Lochristi | - | KFC Voorde-Appelterre | 14:30:00Geannuleerd | N/A |
| 2020-11-14 19:30:0014 november 2020 | SK Sint-Niklaas | - | SK Lochristi | 19:30:00Geannuleerd | N/A |
| 2020-11-11 15:00:0011 november 2020 | SK Lochristi | - | VW Hamme | 15:00:00Geannuleerd | N/A |
| 2020-11-08 14:30:008 november 2020 | FC Lebbeke | - | SK Lochristi | 14:30:00Geannuleerd | N/A |
| 2020-11-01 14:30:001 november 2020 | SK Lochristi | - |  KRC Bambrugge | 14:30:00Geannuleerd | N/A |
| 2020-10-14 20:30:0014 oktober 2020 | KFC Eppegem | - | SK Lochristi | 20:30:00Geannuleerd | N/A |
| 2020-10-10 20:00:0010 oktober 2020 | KVK Svelta Melsele | 2 - 4 | SK Lochristi | 20:00:0020:00 | N/A |
| 2020-10-04 15:00:004 oktober 2020 | SK Lochristi | 2 - 0 | SV Anzegem | 15:00:0015:00 | N/A |
| 2020-09-23 20:00:0023 september 2020 | SK Lochristi | 2 - 4 | SV Oostkamp | 20:00:0020:00 | N/A |
